Search for: All records

Luminescent oxygen sensing is employed for measuring the partial pressure of oxygen diffusing through the skin, named transcutaneous oxygen. Two well-known approaches are intensity- and lifetime-based measurements for assessing transcutaneous oxygen. The lifetime-based technique is preferable as it offers lower susceptibility to optical path changes and reflections compared to the intensity-based method. High-resolution lifetime capturing is critical to accurate transcutaneous oxygen measurements from the human body. This study proposes a miniaturized prototype based on a multimodal analog front end, ADPD4101, and custom firmware. We have demonstrated that the prototype could detect small changes in the lifetime with high resolution, showing its suitability for future human subject tests. We implemented the prototype on a 68 mm × 43 mm printed circuit board (PCB) and consumes the power ×of 39 mW. 

As continuous health monitoring and treatment outside of the traditional clinical environment has become of interest to healthcare providers and governments, the manufacturers of miniaturized wireless biomedical devices have sought to facilitate this idea. Much research has been devoted to smart-and-connected health technologies of various form factors including injectables, implantables, ingestibles, and wearables. Such devices are constrained in physical size, power-consumption budget, storage capacity, and computing power. Yet, they handle sensitive, private information and require trust as they directly affect the health of the patient by means of stimulation and/or drug delivery. In this work, we discuss the role of security as a fundamental component of these devices. We propose a generic layered model to support lightweight and cost-effective implementation of data security and protection mechanisms against possible attacks.